Distinct Pathogenic Genes Causing Intellectual Disability and Autism Exhibit a Common Neuronal Network Hyperactivity Phenotype
Basal ryanodine receptor activity suppresses autophagic flux Vervliet T, Pintelon I, Welkenhuyzen K, Bootman MD, Bannai H, Mikoshiba K, Martinet W, Nadif Kasri N, Parys JB, Bultynck G.(2017) Increased GABAB receptor signaling in a rat model for schizophrenia Selten MM, Meyer F, Ba W, Vallès A, Maas DA, Negwer M, Eijsink VD, van Vugt RW, van […]
Systematic analysis of genetic and phenotypic characteristics reveals antisense oligonucleotide therapy potential for one-third of neurodevelopmental disorders
Basal ryanodine receptor activity suppresses autophagic flux Vervliet T, Pintelon I, Welkenhuyzen K, Bootman MD, Bannai H, Mikoshiba K, Martinet W, Nadif Kasri N, Parys JB, Bultynck G.(2017) Increased GABAB receptor signaling in a rat model for schizophrenia Selten MM, Meyer F, Ba W, Vallès A, Maas DA, Negwer M, Eijsink VD, van Vugt RW, van […]
Compromised transcription-mRNA export factor THOC2 causes R-loop accumulation, DNA damage and adverse neurodevelopment
Basal ryanodine receptor activity suppresses autophagic flux Vervliet T, Pintelon I, Welkenhuyzen K, Bootman MD, Bannai H, Mikoshiba K, Martinet W, Nadif Kasri N, Parys JB, Bultynck G.(2017) Increased GABAB receptor signaling in a rat model for schizophrenia Selten MM, Meyer F, Ba W, Vallès A, Maas DA, Negwer M, Eijsink VD, van Vugt RW, van […]
Loss-of-function variants in the schizophrenia risk gene SETD1A alter neuronal network activity in human neurons through the cAMP/PKA pathway
Basal ryanodine receptor activity suppresses autophagic flux Vervliet T, Pintelon I, Welkenhuyzen K, Bootman MD, Bannai H, Mikoshiba K, Martinet W, Nadif Kasri N, Parys JB, Bultynck G.(2017) Increased GABAB receptor signaling in a rat model for schizophrenia Selten MM, Meyer F, Ba W, Vallès A, Maas DA, Negwer M, Eijsink VD, van Vugt RW, van […]
SETD1A Mediated H3K4 Methylation and Its Role in Neurodevelopmental and Neuropsychiatric Disorders
Basal ryanodine receptor activity suppresses autophagic flux Vervliet T, Pintelon I, Welkenhuyzen K, Bootman MD, Bannai H, Mikoshiba K, Martinet W, Nadif Kasri N, Parys JB, Bultynck G.(2017) Increased GABAB receptor signaling in a rat model for schizophrenia Selten MM, Meyer F, Ba W, Vallès A, Maas DA, Negwer M, Eijsink VD, van Vugt RW, van […]
Cadherin-13 is a critical regulator of GABAergic modulation in human stem-cell-derived neuronal networks
Human Pluripotent Stem Cell-Derived Astrocyte Functionality Compares Favorably with Primary Rat Astrocytes. more info
The emerging role of chromatin remodelers in neurodevelopmental disorders: a developmental perspective
Basal ryanodine receptor activity suppresses autophagic flux Vervliet T, Pintelon I, Welkenhuyzen K, Bootman MD, Bannai H, Mikoshiba K, Martinet W, Nadif Kasri N, Parys JB, Bultynck G.(2017) Increased GABAB receptor signaling in a rat model for schizophrenia Selten MM, Meyer F, Ba W, Vallès A, Maas DA, Negwer M, Eijsink VD, van Vugt RW, van […]
EHMT1 regulates Parvalbumin-positive interneuron development and GABAergic input in sensory cortical areas
Basal ryanodine receptor activity suppresses autophagic flux Vervliet T, Pintelon I, Welkenhuyzen K, Bootman MD, Bannai H, Mikoshiba K, Martinet W, Nadif Kasri N, Parys JB, Bultynck G.(2017) Increased GABAB receptor signaling in a rat model for schizophrenia Selten MM, Meyer F, Ba W, Vallès A, Maas DA, Negwer M, Eijsink VD, van Vugt RW, van […]
The Object Space Task reveals increased expression of cumulative memory in a mouse model of Kleefstra syndrome
Basal ryanodine receptor activity suppresses autophagic flux Vervliet T, Pintelon I, Welkenhuyzen K, Bootman MD, Bannai H, Mikoshiba K, Martinet W, Nadif Kasri N, Parys JB, Bultynck G.(2017) Increased GABAB receptor signaling in a rat model for schizophrenia Selten MM, Meyer F, Ba W, Vallès A, Maas DA, Negwer M, Eijsink VD, van Vugt RW, van […]
Neuronal network dysfunction in a model for Kleefstra syndrome mediated by enhanced NMDAR signaling
Basal ryanodine receptor activity suppresses autophagic flux Vervliet T, Pintelon I, Welkenhuyzen K, Bootman MD, Bannai H, Mikoshiba K, Martinet W, Nadif Kasri N, Parys JB, Bultynck G.(2017) Increased GABAB receptor signaling in a rat model for schizophrenia Selten MM, Meyer F, Ba W, Vallès A, Maas DA, Negwer M, Eijsink VD, van Vugt RW, van […]